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Sunday, December 10

Journaling efforts; PART 3

As you know, this is post 3 to Journaling efforts. If you haven't read the prior ones - go back - now. Otherwise, this is a complete waste of your time. This post will also build onto another post. Until I have the full series done, and put into a particular writing, this series will grow. You will know when it is done when it says "journaling efforts final part."

Let's keep learning. Taking what needs to be learned from industry leaders in this department is wise. 

Thermal Systems and Polymers actually do have a relationship. Thermal-related systems are used to create polymers. Thermal Polarization is what it's called.

Thermal Polymerization - an overview | ScienceDirect Topics says: "The types of polymers determine the way it's produced."

Now, let's skip the subject of polymers being produced to the polymers being used in various ways. Like Polymer Nanoparticles - an overview in ScienceDirect Topics says:

"Polymer nanoparticles have found numerous applications in the biomedical field. Polymer nanoparticles have been used to sequester, purify and concentrate biological molecules. A responsive polymer nanoparticle can be mixed with a complex biological mixture to bind selectively to one target molecule, be isolated from the media, and then release the molecule of interest.184 Polymer nanoparticles have been used for both in vitro and in vivo biosensing.185 Polymer nanoparticles can efficiently act as an artificial extracellular matrix for the culture of various biological tissues.186 However, the primary use of polymer nanoparticles in the biomedical field is as drug delivery vehicles.187–189" (ScienceDirect)

Tandfonline.com gives us a bit more information serving to benefit our understanding. Here is the excerpt. "Nanosized particles have appealing attributes, which have gotten impressive consideration in the last few decades. Polymeric nanoparticles (PNP)s are particles or particulate materials with size at least in the range of 10–100 nm in one dimension. Due to the extremely small size, high volume-surface area ratio, tunable pore, polymer nanoparticles have been used for various applications in different fields,for example, in drug delivery, biosensors, stimuli responsive cargo delivery, nanocomposites, agricultural and environmental applications. The recent development of incorporation of inorganic nanoparticles to polymers permits the alteration of the polymer’s physical as well as chemical properties just as the execution of new highlights in the polymer network. Conjugated polymer nanoparticles are profoundly flexible nano-organized materials that can conceivably discover applications in different branches of science and engineering, for example, optoelectronics, photonics, bio-imaging, bio-detecting and nanomedicine. Their desired sizes and unique properties, biocompatibility and low-toxicity make these materials profoundly appealing for the previously mentioned applications. Polymeric nanoparticles (NPs) are one of the most used nanomaterials for application in nanomedicine. Extreme intrigue lies in the capability of polymeric NPs to alter present-day medication. Usages of polymeric NPs incorporate medication delivery, for example, conjugation and entanglement of medications, prodrugs, stimuli responsive systems, imaging modalities, and theranostics. Biodegradable polymeric nano-structures (BPN) have indicated extraordinary guarantee in various remedial applications, for example, analysis, imaging, sedate delivery, beautifying agents, organ embeds and tissue designing. BPNs display better properties over their separate bulk materials, conquering the restrictions of customary polymers to address numerous significant clinical issues. Besides, the recent developments in research in various area of polymers can empower explicit functionalities of the polymeric nanostructures to be balanced for tunable applications. This concise review emphasizes the various preparative methods of polymeric nanoparticles developed in the last few decades and their uses in various branches of science, e.g., therapeutic, optoelectronic, catalytic and magnetic applications along with several challenging issues concerning the commercialization of emerging polymer-based therapeutics. It also comments on the futuristic uses and applications of polymer nanoparticles in various fields of science in coming decades."

If you aren't taking notes. You are doing yourself a disservice. There is a purpose here. You know. When you take classes in school you must read chapters and answer questions about that chapter. After so many chapters you take a fairly large quiz regarding all the chapters. When its all said and done. You find yourself having to write a paper to discuss all the minute little aspects rolled into one. This is the same thing, friends. Except I am giving this to you for free. No school is going to teach you how to make it through the Great depression. We know that from history. So, don't waste your time. Look at this stuff as if you are learning how the heck your about to weather the financial crisis that's unfolding right now. 

Switching topics isn't about me not being able to stay on topic. It's about a topic having subtopics and so forth. If you don't understand that and you question why I'm taking the path that I'm taking, the explanation here should help you understand the main goal and keep you feeling confident about why you are reading these blog posts.  

Plastic is a huge pollution issue and is also related to polymers. 
Let me explain.

The United Nations

The resolution, based on three initial draft resolutions from various nations, establishes an Intergovernmental Negotiating Committee (INC) which will begin its work this year, aiming to complete a draft legally binding agreement by the end of 2024. That in turn, is expected to present a legally binding instrument, which would reflect diverse alternatives to address the full lifecycle of plastics, the design of reusable and recyclable products and materials, and the need for enhanced international collaboration to facilitate access to technology, to allow the revolutionary plan to be realized. The UN Environment Programme (UNEP) said that it would convene a forum by the end of this year in conjunction with the first session of the INC, to share knowledge and best practices in different parts of the world. 

You can find that forum here.  As a note. These are sites you would do well to look at with a pair of reading glasses, a pen and paper. You should treat these sets of information as if you are going to be tested on them in the coming weeks. The test you will soon take has to do with your finances. The choice is yours to make. Because - believe me or not - something like the Great Depression is unfolding right now before your very eyes. 

Nations sign up to end global scourge of plastic pollution | UN News

Bookmark your calendars for the upcoming "UN Environment Programme Finance Initiative (UNEP FI) is hosting its Regional Roundtable on Sustainable Finance for Latin America and the Caribbean on 30-31 January 2024 in Bogotá, Colombia. This important event will convene 400+ UNEP FI member banks and insurers, investors, supporting institutions, policymakers, academia and civil society to explore the next steps and actions needed to mainstream sustainable finance in the region."  

Also related as a subtopic to polymers:

DARPA Successfully Transitions Synthetic Biomanufacturing Technologies to Support National Security Objectives Living Foundries: 1000 Molecules program testing and evaluation partners from three military branches to continue advanced technology development, all of which is related to polymers. 

"The Defense Advanced Research Projects Agency (DARPA) is soliciting proposals for advancing “Folded Non-Natural Polymers with Biological Function” under a new Broad Agency Announcement for the Fold F(x) program. While the biopharmaceutical industry has realized many outstanding protein and oligonucleotide reagents and medicines by screening large biopolymer libraries for desired function, significant technical gaps remain to rapidly address the full suite of existing and anticipated national security threats in DoD medicine (e.g., diagnostics and remediation strategies for chemical/biological warfare agents and infectious disease threats). The objective of Fold F(x) is to develop processes enabling the rapid synthesis, screening, sequencing and scale-up of folded, non-natural, sequence-defined polymers with expanded functionality. The program will specifically address the development of non-natural affinity reagents that can bind and respond to a selected target, as well as catalytic systems that can either synthesize or degrade a desired target. While non-natural folding polymers (e.g., foldamers) are known, broad utilization of these systems is currently limited because there is no available approach for rapidly developing and screening large non-natural polymer libraries. Fold F(x) will address this technical gap to create new molecular entities that will become future critical reagents in sensor and diagnostic applications, novel medicine leads against viral and bacterial threats, and new polymeric materials for future material science applications."

Defense Advanced Research Projects Agency is the central research and development organization for the US Department of Defense.